繆志江 團(tuán)隊(duì)成員

1、個(gè)人簡(jiǎn)歷

繆志江,，男,，博士，講師,，碩士生導(dǎo)師,。主要從事HDV等常見(jiàn)病原體的分子流行病學(xué)系統(tǒng)研究工作以及抗病毒研究相關(guān)課題，同時(shí)研究領(lǐng)域還涉及HCV,、HEV,、HPgV-1、HPgV-2以及輪狀病毒等病原體的分子檢測(cè)診斷,、遺傳進(jìn)化分析及臨床研究,，具有傳染病學(xué)、病原生物學(xué),、分子流行病學(xué),、分子病毒學(xué)、病毒基因組學(xué)和生物信息學(xué)等多學(xué)科專業(yè)背景,，以及病毒細(xì)胞模型構(gòu)建和藥物篩選評(píng)價(jià)等相關(guān)方法體系和研究經(jīng)驗(yàn)?，F(xiàn)主持云南省科技廳重大專項(xiàng)課題、國(guó)家自然科學(xué)基金青年項(xiàng)目,、云南省科技廳基礎(chǔ)研究面上項(xiàng)目等,。以第一作者或通訊作者在國(guó)際學(xué)術(shù)刊物發(fā)表高水平SCI論文共計(jì)10篇，其中一區(qū)1篇,、二區(qū)5篇,、三區(qū)3篇以及四區(qū)1篇,。

2、聯(lián)系方式

電話：15887862723

電子郵箱：[email protected]

通訊地址：云南省昆明市呈貢區(qū)昆明理工大學(xué)生命科學(xué)學(xué)院分子病毒學(xué)實(shí)驗(yàn)室

3,、教育經(jīng)歷

2010.09-2014.06 云南師范大學(xué),，生命科學(xué)與技術(shù)學(xué)院，生物技術(shù)專業(yè),，學(xué)士

2014.09-2017.06 昆明理工大學(xué),，生命科學(xué)與技術(shù)學(xué)院，生物化學(xué)與分子生物學(xué),，碩士

2017.10-2021.09 Erasmus University Medical Center Rotterdam,，Department of Gastroenterology and Hepatology，Pathogenbiology,，PhD,

4,、工作經(jīng)歷

2022.02-至今昆明理工大學(xué)生命科學(xué)與技術(shù)學(xué)院，碩士生導(dǎo)師

5,、承擔(dān)主要科研項(xiàng)目

1. 云南省科技廳,重大科技專項(xiàng)課題, 202302AA310044-01,云南省不孕不育人群中病原體分布特征和流行規(guī)律研究, 2023-06至2026-05, 447.50萬(wàn)元,在研,主持

2. 國(guó)家自然科學(xué)基金委員會(huì),青年科學(xué)基金項(xiàng)目, 32300142,中國(guó)丁型肝炎病毒地域流行差異性及相關(guān)影響因素研究, 2024-01-01至2026-12-31, 30萬(wàn)元,在研,主持

3. 云南省科技廳,基礎(chǔ)研究專項(xiàng), 202401AT070407,乙型肝炎病毒天然重組包膜蛋白對(duì)丁型肝炎病毒增殖過(guò)程的影響及機(jī)制研究, 2024-03至2027-02, 10萬(wàn)元,在研,主持

4. 云南省第一人民醫(yī)院,，臨床病毒學(xué)重點(diǎn)實(shí)驗(yàn)室開(kāi)放課題重點(diǎn)項(xiàng)目，202205AG070061-BD-05感染性不孕不育相關(guān)肝炎病毒分子診斷方法的建立及大規(guī)模臨床應(yīng)用,；2024-08至2027-07, 10萬(wàn)元,在研,主持

6,、代表論文、專利和專著

1. Xiaoyan Xu1, Yunjiao Luo1, Canlin He, Ziqin Dian, Hongying Mi, Jinghui Yang, Yue Feng, Zhijiang Miao*and Xueshan Xia*, Increased Risk of Neurological Disease Following Pediatric Rotavirus Infection: A Two-Center Case-Control Study.Journal of Infectious Diseases, 2023 May 29;227(11):1313-1321.（IF=7.8; JCR Q1區(qū)/醫(yī)學(xué)二區(qū)Top）

2. Zhijiang Miao, Shaoshi Zhang, Xumin Ou, Shan Li, Zhongren Ma, Wenshi Wang, Maikel P Peppelenbosch, Jiaye Liu* and Qiuwei Pan*, Estimating the Global Prevalence, Disease Progression, and Clinical Outcome of Hepatitis Delta Virus Infection.Journal of Infectious Diseases, 2020 Apr 27;221(10):1677-1687.（IF=5.2; JCR Q1區(qū)/醫(yī)學(xué)二區(qū)Top）

3. Zhijiang Miao and Qiuwei Pan*. Revisiting the estimation of hepatitis D global prevalence,Journal of Hepatology, 2020 Nov;73(5):1279-1280.（Letter,IF=25.1; JCR Q1區(qū)/胃腸肝病學(xué)一區(qū)Top）

4. Zhijiang Miao, Ruyi Zhang, Peifa Yu, Yang Li, Qiuwei Pan* and Yunlong Li*. The macrolide antibiotic azithromycin potently inhibits hepatitis E virus in cell culture models,International Journal of Antimicrobial Agents, 2021 Sep;58(3):106383. (IF=15.4; JCR Q1醫(yī)學(xué)二區(qū))

5. Ziqin Dian, Yi Sun, Guiqian Zhang, Ya Xu, Xin Fan, Xuemei Yang, Qiuwei Pan, Maikel Peppelenbosch andZhijiang Miao*. Rotavirus-related systemic diseases: clinical manifestation, evidence and pathogenesis,Critical Reviews in Microbiology, 2021 Sep;47(5):580-595.（IF=7.4; JCR Q1區(qū)/微生物學(xué)二區(qū)）

6. Zhijiang Miao, Shaoshi Zhang, Zhongren Ma, Mohamad S. Hakim, Wenshi Wang, Maikel P. Peppelenbosch and Qiuwei Pan*, Recombinant identification, molecular classification and proposed reference genomes for hepatitis delta virus,Journal of Viral Hepatitis, 2019 Jan;26(1):183-190.（IF=3.6; JCR Q2區(qū)/病毒學(xué)二區(qū)）

7. Zhijiang Miao1, Zhenrong Xie1, Li Ren, Qiuwei Pan*. Hepatitis D: advances and challenges,Chinese Medical Journal, 2022 Apr 5;135(7):767-773. (Invited Review). (IF=6.2; JCR Q3/醫(yī)學(xué)三區(qū))

8. Zhijiang Miao, Yunlong Li, Peifa Yu, Bingting Yu, Maikel P. Peppelenbosch and Qiuwei Pan*, The dynamics of hepatitis delta virus prevalence and its potential association with hepatitis B virus vaccination,Clinics and Research in Hepatology and Gastroenterology, 2021 May;45(3):101677.（IF=3.2; JCR Q3區(qū)/胃腸肝病學(xué)四區(qū)）

9. Zhijiang Miao1, Li Gao1, Yindi Song, Ming Yang, Mi Zhang, Jincheng Lou, Yue Zhao, Xicheng Wang, Yue Feng*, Xingqi Dong* and Xueshan Xia*. Prevalence and clinical impact of human pegivirus-1 infection in HIV-1-infected individuals in Yunnan, China.Viruses, 2017 Feb 15;9(2):28.（IF=3.8; JCR Q2區(qū)/微病毒學(xué)三區(qū)）

10. Zhijiang Miao1, Zhenrong Xie1, Jing Miao, Jieyu Ran, Yue Feng* and Xueshan Xia*, Regulated Entry of Hepatitis C Virus into Hepatocytes. Viruses, 2017 May 9;9(5):100.（IF=3. 8; JCR Q2區(qū)/微病毒學(xué)三區(qū)）

11. Peifa Yu,Zhijiang Miao, Yang Li, Maikel P. Peppelenbosch, Qiuwei Pan*. cGAS-STING Effectively Restricts Murine Norovirus Infection But Antagonizes the Antiviral Action of N-terminus of RIG-I in Mouse Macrophages.Gut Microbes, 2021 Jan-Dec;13(1):1959839. (IF=9.4; JCR Q1區(qū)/醫(yī)學(xué)一區(qū)Top)

12. Yunlong Li,Zhijiang Miao, Pengfei Li, Ruyi Zhang , Denis E Kainov , Zhongren Ma , Robert A de Man, Maikel P Peppelenbosch and Qiuwei Pan*, Ivermectin effectively inhibits hepatitis E virus replication, requiring the host nuclear transport protein importin α1.Archives of Virology, 2021.（IF=2.6; JCR Q3區(qū)/病毒學(xué)四區(qū)）

13. Ling Wang, Jiaye Liu,Zhijiang Miao, Qiuwei Pan* and Wanlu Cao*. Lipid droplets and their interactions with other organelles in liver diseases.The International Journal of Biochemistry & Cell Biology,，2021.（IF=5.1; JCR Q2區(qū)/細(xì)胞生物學(xué)三區(qū)）

14. Peifa Yu, Yang Li, Yunlong Li,Zhijiang Miao, Maikel P. Peppelenbosch and Qiuwei Pan*. Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.Journal of Biological Chemistry, 2020.（IF=5.2; JCR Q2區(qū)/生物學(xué)二區(qū)Top）

15. Peifa Yu, Yang Li, Yunlong Li,Zhijiang Miao, Yining Wang, Maikel P. Peppelenbosch and Qiuwei Pan*. Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response.Antiviral Research, 2020.（IF=6.0; JCR Q1/2區(qū)/病毒學(xué)藥學(xué)二區(qū)）

16. Xumin Ou, Buyun Ma, Ruyi Zhang,Zhijiang Miao, Anchun Cheng, Maikel P. Peppelenbosch and Qiuwei Pan*. A simplified qPCR method revealing tRNAome remodeling upon infection by genotype 3 hepatitis E virus.FEBS letters, 2020.（IF=4.1; JCR Q3區(qū)/病毒學(xué)四區(qū)）

17. Yindi Song1, Yue Feng1,Zhijiang Miao, Binghui Wang, Ming Yang, A-Mei Zhang, Li Liu and Xueshan Xia*. Near-Full- Length Genome Sequences of a Novel Hiv-1 Circulating Recombinant Form, Crf01_Ae/B'/C（Crf78_Cpx）, in Yunnan, China.AIDS research and human retroviruses, 2016.（IF=2.2; JCR Q4區(qū)/病毒學(xué)四區(qū)）

18. Yanping Li1, Jing Miao1,Zhijiang Miao, Yindi Song, Min Wen, Ya Zhang, Shimin Guo, Yuan Zhao, Yue Feng* and Xueshan Xia*. Identification of a Novel HIV Type 1 Circulating Recombinant Form（CRF86_BC）Among Heterosexuals in Yunnan, China.AIDS research and human retroviruses, 2016.（IF=2.2; JCR Q4區(qū)/病毒學(xué)四區(qū)）

19. Li Ren, Binghui Wang,Zhijiang Miao, Pan Liu, Shiyi Zhou, Yun Feng, Shuting Yang, Xueshan Xia* and Kunhua Wang*, A correlation analysis of HHV infection and its predictive factors in an HIV-seropositive population in Yunnan, China,Journal of Medical virology, 2019.（IF=2.3; JCR Q4區(qū)/病毒學(xué)四區(qū)）

7,、獲得獎(jiǎng)勵(lì)

1. 2022.11“農(nóng)行杯”第八屆云南省互聯(lián)網(wǎng)+大學(xué)生創(chuàng)新創(chuàng)業(yè)大賽金獎(jiǎng)指導(dǎo)教師。