王海燕

學(xué)歷：博士

專家類別（職稱）：助理研究員

郵箱：[email protected]

通訊地址：云南省昆明市呈貢區(qū)雨花街道春融西路1168號

郵編：650500

簡歷

教育經(jīng)歷

（1）2019-09至2023-06,，中南大學(xué)，病理學(xué)與病理生理學(xué),，博士

（2）2016-09至2019-06,，中南大學(xué)，藥理學(xué),，碩士

（3）2012-09至2016-06,，南昌大學(xué)，制藥工程,，學(xué)士

工作經(jīng)歷

2023-09-至今,，昆明醫(yī)科大學(xué)，生物醫(yī)學(xué)工程研究院,，助理研究員

研究方向

G蛋白偶聯(lián)受體與消化道腫瘤的分子機(jī)制與靶向藥物研究

研究成果（論文,、專利、專著等）

[1] Wang H, Cheng Y, Mao C, et al. Emerging mechanisms and targeted therapy of ferroptosis in cancer. Mol Ther. 2021 Jul 7;29(7):2185-2208.

[2]Wang HY#, Yu P#, Chen XS, et al. Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction. Acta Pharmacol Sin. 2022 Jun;43(6):1594-1604.

[3] Yu P#,Wang HY#, Tian M, et al. Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro. Acta Pharmacol Sin. 2019 Sep;40(9):1237-1244.

[4] Chen L, Cai QD, Yang R,Wang HY, Huli Ling, et al. GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15): e2219585120.

[5] Yan BK, Guo JX, Wang ZL, Jieling N,Haiyan W, et al. The ubiquitin-specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression. MedComm (2020). 2023 Jul 22;4(4):e337.

[6] Yao L, Guo JX, Chen JL, Sun JY, Wang HY, Peng X, et al. GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer. Signal Transduct Target Ther (IF= 38.104). 2023 Feb 1;8(1):48.