一,、個(gè)人簡(jiǎn)介

教授,，博士，博士研究生導(dǎo)師,，云南省中青年學(xué)術(shù)技術(shù)帶頭人,，“興滇英才”支持計(jì)劃教學(xué)名師,，云南省卓越青年教師，國(guó)家一流本科課程《法醫(yī)物證學(xué)》和云南省研究生優(yōu)質(zhì)課程《實(shí)用DNA分析技術(shù)》負(fù)責(zé)人,，云南省法醫(yī)學(xué)博導(dǎo)團(tuán)隊(duì)和昆明醫(yī)科大學(xué)法醫(yī)分子鑒定科技創(chuàng)新團(tuán)隊(duì)負(fù)責(zé)人,，現(xiàn)昆明醫(yī)科大學(xué)研究生院院長(zhǎng)。主持國(guó)家自然科學(xué)基金4項(xiàng),、國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題2項(xiàng),、省科技廳項(xiàng)目3項(xiàng)；以第一/通訊作者發(fā)表學(xué)術(shù)論文70余篇,，其中SCI收錄論文31篇,；獲省科技進(jìn)步三等獎(jiǎng)1項(xiàng)。參編國(guó)家規(guī)劃教材1部,，獲省教學(xué)成果一等獎(jiǎng)1項(xiàng),，省級(jí)教學(xué)創(chuàng)新競(jìng)賽一等獎(jiǎng)和二等獎(jiǎng)各1項(xiàng)。指導(dǎo)研究生獲云南省教育廳科學(xué)研究基金2項(xiàng)，昆明醫(yī)科大學(xué)研究生創(chuàng)新基金4項(xiàng),。

二,、主要研究方向

法醫(yī)遺傳學(xué)；精神疾病及暴力攻擊行為的遺傳基礎(chǔ)及分子機(jī)制

三,、近五年主要承擔(dān)科研項(xiàng)目

1.國(guó)家自然科學(xué)基金委員會(huì),，地區(qū)基金，31660310,，HPA軸基因啟動(dòng)子區(qū)多態(tài)性及其甲基化與軀體攻擊行為相關(guān)性研究,，2017.01至2020.12，38萬(wàn)元,，結(jié)題,，主持

2.國(guó)家自然科學(xué)基金委員會(huì)，地區(qū)基金,，31860300,，外周血NR3C1和NR3C2基因DNA甲基化、基因表達(dá)及交互作用與精神分裂癥體力攻擊行為的相關(guān)性研究,，2019.01至2022.12,，38萬(wàn)元，結(jié)題,，主持

3. 國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題,2018YFC0807201-4,曼陀羅,、雪上一枝蒿、劇毒鵝膏菌主要毒性成分體內(nèi)代謝與中毒關(guān)聯(lián)性研究, 2018.07至2021.06,82萬(wàn),結(jié)題,，主持

4.國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題2022YFC33410001-2,，云南地區(qū)人群高精度Y染色體系統(tǒng)發(fā)育譜系樹構(gòu)建及其法醫(yī)學(xué)應(yīng)用研究，2022.10至2025.09,，80萬(wàn),，在研，主持

四,、近五年代表性學(xué)術(shù)成果

Chen Xuanyu#, Qing Lili#, Zou Tiantian#, Wang Jia, Yin Wensa, Wang Zhiyong, Cheng Tiantian, Lu Yumei, Hu Liping*, Liu Linlin*, Nie Shengjie*. An analysis of POMC gene methylation and expression in patients with schizophrenia. International Journal of Developmental Neuroscience. 2024 May;84 (3), 208-216

Lu Yumei#, Qing Lili#, Hu Liping#, Yin Wensa, Chen Xuanyu, Wang Zhiyong, Cheng Tiantian, Wang Jia, Liu Linlin*, Nie Shengjie*. Hypomethylation and high expression of the TMTC1 gene in patients with schizophrenia. Asian journal of psychiatry. 2024 Jan 9;93:103922.

Qing Lili#, Xiong Peng#, Lu Yumei, Jiang Hongyan*, Nie Shengjie*. Sex-dependent association of DNA methylation in the coding region of the corticotropin-releasing hormone gene and schizophrenia spectrum disorder. Annal of Human Biology. 2023 Feb;50(1):1-8.

Linlin Liu#, Yi Hu#,Yumei Lu, Liping Hu*,Changqin Gao*, Shengjie Nie*. Sex-dependent DNA hypermethylation of SLC6A4 in patients with schizophrenia. Neuroscience Letters. 2022 ,769, 136394.

Linlin Liu#, Jiahui Yuan#, Lei Miao, Renwu Huang, Xiufeng Zhang*, Shengjie Nie*, Liping Hu*.Genetic polymorphisms of 16 X-STR loci analyzed in the Han population of Yunnan Province, Southwest China.Legal Medicine,2022,54:101974

Xiufeng Zhang#, Xiaokun Yuan #, Yangzhi Huang , Jinyong Yao , Jian Zhang ,Jiameng Dai, Linlin Liu *, Shengjie Nie *, Liping Hu*.Forensic genetic polymorphisms of 16 X-STR loci in the Yunnan Miao population and their relationship to other Chinese groups. Legal Medicine,2021,53:101961

Linlin Liu#, Jinyong Yao#, Yangzhi Huang, Lei Gao, Jiameng Dai, Xiaokun Yuan, Xiufeng Zhang*, Shengjie Nie*,， Liping Hu*. Genetic polymorphisms of 16 X-STR loci in the Hani population from Southwest China, Forensic Sciences Research, 2021;1-6

LiliQing*,ChangqingGao*,AicenJi,Xin Lü, LiZhou#,ShengjieNie#.Association of mineralocorticoid receptor gene (NR3C2) hypermethylation in adult males with aggressive behavior. Behavioural Brain Research, 2021 Feb 1;398:112980

Linlin Liu#, Jiajue Li#, Lili Qing, Ming Yan, Gen Xiong, Xinqing Lian, Liping Hu*, Shengjie Nie*. Glucocorticoid Receptor Gene (NR3C1) Is Hypermethylated in Adult Males With Aggressive Behaviour. International Journal of Legal Medicine. 2021;135(1):43-51.

五,、聯(lián)系郵箱: [email protected]