一,、個人簡介：

李利華，男,，二級教授,，博士生導師，博士后合作導師,。昆明醫(yī)科大學黨委常委,、副校長，國家衛(wèi)生健康委毒品依賴和戒治重點實驗室主任,。享受國務院政府特殊津貼,，教育部高等學校法醫(yī)學類專業(yè)教學指導委員會委員，云南省中青年學術和技術帶頭人,，云南省委聯(lián)系專家,，司法部司法鑒定能力驗證技術專家。現(xiàn)擔任全國高等法醫(yī)學教育研究會常務理事,、云南省高等教育學會副會長,、昆明醫(yī)科大學校友會副理事長。獲中華人民共和國司法部法律服務工作者先進個人,、全國司法鑒定先進個人等榮譽稱號,。

從事高校法醫(yī)學教育、科研和司法鑒定工作35年。主要研究領域為毒品成癮與戒斷干預技術,、法醫(yī)病理學和毒理學損傷機制研究,，在國內(nèi)法醫(yī)學和禁毒研究領域有較大學術影響力和知名度。主持承擔國家自然科學基金項目5項,，主持承擔省科技計劃項目9項，參與國家和省級科技計劃項目11項,。以第一作者或通訊作者發(fā)表學術論文100多篇,，SCI收錄24篇。主編,、副主編和參編國家級規(guī)劃教材,、專著15部。獲云南省科技進步三等獎5項,，獲云南省教學成果一等獎1項,、二等獎2項。

二,、主要研究方向：

毒品成癮與戒斷干預技術,、法醫(yī)病理學和毒理學損傷機制研究。

三,、近五年主要承擔科研項目：

1.國家自然科學基金面上項目,《TRPV1對甲基苯丙胺依賴記憶印跡的調(diào)控機制及大麻二酚的干預作用》（2024.01-2027.12）,，主持。

2.國家自然科學基金地區(qū)項目,，《甲基苯丙胺成癮者腦功能磁共振檢測和神經(jīng)毒性損害機制》（2019.01-2022.12）,，主持。

四,、近五年代表性學術成果：

1.Wenjuan Dong#, Jia Wan# , Hao Yu , Baoyu Shen , Genmeng Yang , Qianyun Nie , Yan Tian , Lixiang Qin, Chunhui Song , Bingzheng Chen, Lihua Li,* Shijun Hong.* Nrf2 protects against methamphetamine-induced nephrotoxicity by mitigating oxidative stress and autophagy in mice[J].Toxicology Letters, 384 (2023) 136-148

2. Baoyu Shen; Dongxian Zhang; Xiaofeng Zeng; Lina Guan; Genmeng Yang; Liu Liu; Jian Huang;Yuanyuan Li; Shijun Hong*; Lihua Li* ; Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway, Psychopharmacology, 2022, 239(5):1521-15372.

3.Baoyu Shen; Ruilin Zhang; Genmeng Yang; Yanxia Peng; Qianyun Nie; Hao Yu; Wenjuan Dong;Bingzheng Chen; Chunhui Song; Yan Tian; Lixiang Qin; Junjie Shu; Shijun Hong*; Lihua Li*;Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2, Frontiers in Pharmacology, 2022, 13: 972828.

4.Genmeng Yang; Juan Li; Chi-Kwan Leung; Baoyu Shen; Chan Wang; Yue Xu; Shucheng Lin;Shuwei Zhang; Yi Tan; Huijie Zhang; Xiaofeng Zeng*; Shijun Hong*; Lihua Li *; Methamphetamine and HIV-1 Tat proteins synergistically induce microglial autophagy via activation of the Nrf2/NQO1/HO-1 signal pathway, Neuropharmacology, 2022, 220: 109256

5.Hao Yu; Yanxia Peng; Wenjuan Dong; Baoyu Shen; Genmeng Yang; Qianyun Nie; Yan Tian;Lixiang Qin; Chunhui Song; Bingzheng Chen; Yongna Zhao; Lihua Li*; Shijun Hong* ; Nrf2 attenuates methamphetamine-induced myocardial injury by regulating oxidative stress and apoptosis in mice, Human Experimental Toxicology, 2023, 42: 1-11

6. Qianyun Nie; Wenjuan Dong; Baoyu Shen; Genmeng Yang; Hao Yu; Ruilin Zhang; Yanxia Peng;Yang Yu; Shijun Hong*; Lihua Li* ; Cannabidiol attenuates methamphetamine-induced cardiac inflammatory response through the PKA/CREB pathway in rats, Annals of Translational Medicine, 2022, 1(18): 985-985

7.Gen-Meng Yang#; Lu Li#; Feng-Lin Xue; Chen-Li Ma; Xiao-Feng Zeng; Yong-Na Zhao; Shi-Jun Hong*; Li-Hua Li*; The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line, Neurotoxicity Research, 2020, 37: 926-935.

8.C-L Ma#; L Li#; G-M Yang; Z-B Zhang; Y-N Zhao; X-F Zeng; D-X Zhang; Y Yu; Z-J Shi; Q-W Yan; L-H Li*; S-J Hong*; Neuroprotective effect of gastrodin in methamphetamine-induced apoptosis through regulating cAMP/PKA/CREB pathway in cortical neuron, Human and Experimental Toxicology, 2020, 39(8): 1118–1129.

五,、聯(lián)系郵箱:[email protected]